Currently, equal status of political leadership participation of women is a prerequisite for democratic governance. However, women continue to be marginalized from the political sphere due to attitudinal social and institutional challenges. The purpose of this study was to identify the women’s participation in political leadership in Ganta Afeshum Woreda. A case study research design was used to conduct the study. A qualitative method was also applied to undertake in depth study using non-probability sampling by which samples officials were taken from the public sectors in the Woreda particularly by purposive sampling technique. Interview and focus group discussion were used to collect data that were qualitatively analyzed by thematic data analyses technique. The results indicated that the women’s political leadership participation in Ganta Afeshum Woreda has a low status as women were underrepresented in the various leadership positions. Although some strategies existed in the sectors, they haven’t been implemented in reality. The underrepresentation of women was attributed to the various challenges traced to the sectors, the women themselves and the community. Regarding the basic finding and conclusions the study recommended that to empowering women’s participation in political leadership the woreda have to providing the education facility ,training ,giving awareness via media and different programs at the local level should be designed a means to overwhelm the problem of gender inequality. Key words; Women, political leadership, Ganta Afeshum, Woreda