This study examines green supply chain practice impact on green supply chain performance. To come up with possible theoretical and empirical insights as how to large manufacturing firms increase their green performance. The independent variable (GSC activities) was grouped into 4 practices: Green purchasing, Eco-design, legislation and regulation, reverse logistics, whereas dependent variable includes environmental, economic, and intangible performances. Quantitative research approach with explanatory research design was employed. By using stratified proportional sampling a sample of 203 dataset was collected from 5 large manufacturing firms of Bahir Dar town; and used to test the proposed research hypotheses. Preliminary assumptions were tested. Convergent and discriminate validity were used to examine the construct validity. Measurement and structural model fit were tested. All four components had direct relationship with environmental performance. Except reverse logistics other independent variables had a relationship with economic and intangible performances. Legislation and regulation is considered as a priority leading to enhance the intangible performance. While reverse logistics indicated a low level of adoption and having little significance impact to green performance. The results of this study suggested that organizations need to be aware that green supply chain activities may impact on their green performance.