Upland rice (NERICA-4) is a highly valued crop in Northwestern Ethiopia. However, its productivity is very low due to insufficient nitrogen supply, inappropriate sources and nitrogen application time. Therefore, a field experiment was conducted on farmers’ field at Fogera District in Northwestern Ethiopia during 2018 cropping season to determine the right sources, rates and timing of Nitrogen application to maximize the productivity of upland rice. A factorial combination of three nitrogen rates (69, 103.5, and 138 kg N ha-1 ), three N application times (T1=1/3 at planting, 1/3 at tillering and 1/3 at PI (panicle initiation), T2= 1/3 15 DAS (days after sowing), 1/3 at PI and 1/3 at Heading, and T3= 1/3 15 DAS and 2/3 at PI (NTA3)) and two N fertilizer sources, urea stable (US) (46% N) and common urea (CU) (46% N)) were laid out in randomized complete block design with three replications. Phenological, growth and yield related data were collected and analyzed using SAS V 9.0. The ANOVA result of this experiment showed that dry biomass and grain yield were significantly affected by the main effects of nitrogen source, rates and time of application. Whereas most yield and yield related components of upland rice were influenced by interaction effects of N sources, rates and application times. The highest grain yield (6.16 t ha-1 ) was recorded in common urea (CU) Nitrogen source, at a rate of 69 kg N ha -1 , and when the N was applied at 1/3 at 15 DAS + 2/3 at PI (NTA3). The partial budget analysis revealed that the combination of common urea (CU), at a rate of 69 kg N ha -1 , and when the N was applied at 1/3 at 15 DAS + 2/3 at PI (NTA3) is economically feasible with maximum net benefit of 93,393.53 ha-1 ETB as compared to others. Therefore, it can be concluded that this treatment is recommended for enhancing NERICA-4 rice productivity in the study area, Fogera district. However, it needs to repeat the research in a number of sites and seasons to come up with strong recommendations. Key words: Biomass yield, Common urea, NERICA-4, Stable urea, Total tillers