This study was undertaken in the Lake Tana sub basin having a total area of 15,096km2 for the influence of different watershed geomorphic characteristics on suspended sediment yield. Twelve gauged watersheds were selected from the total basin in the catchment area and 29 Watershed geomorphic and topographic characteristics were extracted from DEM, using empirical equations supported by ArcGIS software. The feasibility of using different topographic characteristics include (primary, secondary and compound), geomorphic characteristics (watershed shape, relief parameter and stream networks), hydrologic characteristics (ran fall, flow and suspended sediment yield), on identifying of the influencing parameters and modeling of suspended sediment yield. Partial least square analysis was applied Because of the high codependence among those characteristics to identify the linkages between the suspended sediment yields and composed of 29 selected watershed characteristics.10 significant predictors (area, basin length, stream order perimeter, sediment transport capacity index, basin relief, profile curvature, hypsometry integral rainfall, and relative relief, were selected based on high variable important for the projection (VIP), correlation and regression coefficient criteria. Those variables with high VIP, correlation and regression coefficient values are the most relevant for explaining the response variable. The three equations were developed using the most influencing factors (area, basin length and stream order). The aim of this study provides the information to understand the role of geomorphic characteristics in determining the internal dynamics of suspended sediment yield in the watersheds.