Castro intestinal parasites in fections represent a major public health problem in poor and developing countries. The prevalence and burden of these diseases are high in school going children. The effective control of intestinal helminth infections requires determining their prevalence and identifying the associated riskfactors, particularly among high-risk groups. The objective of this study was to determine the prevalence and associated risk factors for gastro intestinal parasite infections in Tacharmacho woreda, northwest Erhiopia. A cross-secrional studv was conducted from November 2010 to January 2011. Four hundred twenty Mo studv subjects were selected using systematic sampling method. Structured questionnaires were used to collect information on associated risk factors for gastro intestinal parasite infections. Stool samples were collected and examined for intestinal parasites by direct saline thin smear technique. The overall prevalence of intestinal parasites infections was 57.8% (2441422). The most frequent intestinal parasites were S. mansoni, hookworm and G.lambia with prevalence of 37% (l 561422). 17.3% (731422) and 8.5% (361422), respectivelv. The prevalence of other parasites infection were: E. histolvtica J 6(3. 8%), H. nana 11 (2. 6 %), and A. Iumbricoides 6 ( 1.4%). Intestinal parasites infection showed the prevalence to be more than 50% in five of the six kebeles studied. The highest prevalence of intestinal parasite was observed in the age group 6-10 years (76. 1ro,L. followed by 11-16 vears old (71. 4~) and the lowest prevalence was recorded in individuals age above 40 years (34. 6%). Males were more infected with gastro intestinal p~rasites than females with prevalence (!f 63.2% and 50.3%, respectively (p<0.05). The majority, J 96 (80. 3%) of the residents had single infection and 43 (10. 2%) had double intestinal parasites infection and [ive (1.2%) had triple infections. The most frequent combinations of intestinal parasite diagnosed in single patients were double infection of S. mansoni and hookworm 3 7 (8 8%) Based on these results, it can be concluded that gastro intestinal parasite infections were important health problems of Tach-Annachiho woreda. Health education is ... ABSTRACT recommended for controlling the transmission ofgastro intestinal parasites infection. Castro intestinal parasites infections represent a major public health problem in poor and developing countries. The prevalence and burden of these diseases are high in school going children. The effective control of intestinal helminth infections requires determining their prevalence and identifying the associated riskfactors, particularly among high-risk groups. The objective of this study was to determine the prevalence and associated risk factors for gastro intestinal parasite infections in Tacharmacho woreda, northwest Erhiopia. A cross-secrional studv was conducted from November 2010 to January 2011. Four hundred twenty Mo studv subjects were selected using systematic sampling method. Structured questionnaires were used to collect information on associated risk factors for gastro intestinal parasite infections. Stool samples were collected and examined for intestinal parasites by direct saline thin smear technique. The overall prevalence of intestinal parasites infections was 57.8% (2441422). The most frequent intestinal parasites were S. mansoni, hookworm and G.lambia with prevalence of 37% (l 561422). 17.3% (731422) and 8.5% (361422), respectivelv. The prevalence of other parasites infection were: E. histolvtica J 6(3. 8%), H. nana 11 (2. 6 %), and A. Iumbricoides 6 ( 1.4%). Intestinal parasites infection showed the prevalence to be more than 50% in five of the six kebeles studied. The highest prevalence of intestinal parasite was observed in the age group 6-10 years (76. 1ro,L. followed by 11-16 vears old (71. 4~) and the lowest prevalence was recorded in individuals age above 40 years (34. 6%). Males were more infected with gastro intestinal p~rasites than females with prevalence (!f 63.2% and 50.3%, respectively (p<0.05). The majority, J 96 (80. 3%) of the residents had single infection and 43 (10. 2%) had double intestinal parasites infection and [ive (1.2%) had triple infections. The most frequent combinations of intestinal parasite diagnosed in single patients were double infection of S. mansoni and hookworm 3 7 (8 8%) Based on these results, it can be concluded that gastro intestinal parasite infections were important health problems of Tach-Annachiho woreda. Health education is recommended for controlling the transmission ofgastro intestinal parasites infection.