Primary school children are one of the highly susceptible groups to intestinal parasitic infections. Intestinal parasitic infections (IPIs) are prevalent through the tropics and sub tropics, especially among poor countries including Ethiopia. The effective prevention and control of intestinal protozoa and helminthic infections require identification of local risk factors. The aim of this study was to assess the prevalence of intestinal parasitic infections and associated risk factors among primary school children in Yifag and Agidkirigna inLibokemkem district, Northwest Ethiopia. The study was conducted from November 2017 to June 2018, involving 403 students those selected by using systematic random sampling technique from two primary schools,Yifag and Agidkirigna in Libokemkem district. The stool samples were examined microscopically using direct wet mount and formal-ether concentration technique. Structured questionnaire was used to obtained relevant information on socio-demographic data. Data was analyzed by SPSS version 20 software using Chi-square test, binary logistic regression. Out of 403 stool samples examined, 108(26.8%) infected with intestinal parasitic protozoan and helminthic parasites.The overall protozoan infection was 33(8.2%) while helmithic infection was 75(18.6%). A total of eight species were identified; A.lumbricoides (7%), E.histolytica (6.2%), H.nana (5.5%), S.mansoni (2.2%), G.lamblia (2%), Taenia species (1.7%), Hookworm (1.5%) and E.vermicularis (0.7%).Types of infection in the study subjects were single infection. Prevalence rate of intestinal parasitic infections had significantly associated with eating raw, under cooked, unwashed vegetables and fruits; the habit of using toilet, latrine availability of the area; shoe wearing habit of the students, residential area, educational status of the mothers (p<0.05). On the other hand sex, grade level, age, trimming fingernails, and hand washing habit before meal, bathing or swimming in the water bodies were not significantly associated with IPIs (P>0.05). The high prevalence of intestinal parasitic infections in the school children implies the need of health education in relation to encouraging shoe wearing habit, hand washing habit before meal and after toilet, deworming the school children, encouraging the habit of using toilet, building enough toilets in the school and at their home, improvement of safe water supply, health facilities, that may restrict children from defecating in the open field and near river/streams and it contributes to reduce and prevent (control) the rate of transmission of intestinal parasitic infections. Key words: Yifag, Agidkirigna, Intestinal parasitic infections, Prevalence, School children