V()LTAMMETRIC DETE.RMINATION OF ASCORBIC ACID CONTENT IN PHAllM . .\.C'EUTICAL TABLETS  ? USING CARBON PASTE ELECTRODE

ZELALEM, BITEW

dc.contributor.author	ZELALEM, BITEW
dc.date.accessioned	2018-06-28T04:30:06Z
dc.date.available	2018-06-28T04:30:06Z
dc.date.issued	2018-06-20
dc.identifier.uri	http://hdl.handle.net/123456789/8795
dc.description.abstract	Ascorbic acid is one of the most import am ingredients of jOOd. fruits. and mm1r pharmaceutical la/!el.\ and preparations. A square w1n•e voltammetric technique using carbon paste electrode was developed for the determination of ascorbic acid content in pharmaceutical tablets. Voltammetrlc measurements were made in a potential range of -100 mV tolOOO mV using a scan • ' <, rate of 50 mVi''s. effect ofp}! was studied on the determination ofascorbic acid in the range o/ 0. 5-6. The irfluence o.f lhl! operational parameters like square wa>'e frequency, square wave amplitude, and step potcn'&il was investigated. The accumulation potential and accumulation time were also optimized. A linear voliammetrlc response was obtained in the concentration rmif{e of teur': 6x10·• with a detection limi: (l.ODj of JJ6xlo-6 Mand limit of quantifiauion fLOQj <1/ 5. 86.i· I 0'6 M The method developed was applied for the determination <if ascorbic acid in phamtbcewical tablets. The reliability of the proposed	en_US
dc.language.iso	en	en_US
dc.subject	chemistry	en_US
dc.title	V()LTAMMETRIC DETE.RMINATION OF ASCORBIC ACID CONTENT IN PHAllM . .\.C'EUTICAL TABLETS ? USING CARBON PASTE ELECTRODE	en_US
dc.type	Thesis	en_US