| dc.description.abstract |
Ihe ctccrrochcmical oxidation of salicylic acid (SA) ·has been studied on a glassy carbon
electrode using cyclic vo lrammerry and differential pulse voltarrunctric (DPV) method. S,\
gives a single irreversible oxidation wave over the wide pH range studied. The
irreversibility of the electrode process was verified by different criteria, The mechanism of
oxidation is discussed. Lsing differential pulse voluumnctry, SA yielded a wclldcfincd
volrammctric response in Britton Robinson buffer solution, pH 1.37 at a peak poteruial or
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94() mV (versus .Ag!AgCI). The method was linear over the SA concentration range: 21)
1;0 ~rg mr' The method was successfully applied for the analysis of SA as a hydrolysis
product, in solid pharmaceutical formulations containing acetylsalicylic acid (ASA) . |
en_US |