SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITIES OF MONONUCLEAR COPPER (II) COMPLEX OF 1, 10-PHENANTHROLEIN AND ACITAMID LIGANDS

WONDIE, MEKONNEN

dc.contributor.author	WONDIE, MEKONNEN
dc.date.accessioned	2017-10-13T05:19:28Z
dc.date.available	2017-10-13T05:19:28Z
dc.date.issued	2017-10-13
dc.identifier.uri	http://hdl.handle.net/123456789/7976
dc.description.abstract	In this thesis, the synthesis, characterizations (conductivity measurements, melting point determination ,chlorideestimation,FT-IR, UV-Vis, ICP-OES) and biological activities of a new mononuclear copper(II) complex of the type [Cu(phen)2CH3CONH2]2+2Cl-.H2O, where phen=1,10-phenanthroline is described. The in-vitro antimicrobial study result was also compared with the commercially available antimicrobial activities such as, Cotrimoxazole, Penicillin, Tetracycline, ciprofloxacin and Ampicillin as standard antibiotics to determine the antimicrobial activities of the complexes. The synthesized complex demonstrated better activities on staphylococcus aurous and Klebsella pneumonia. Thus, after cytotoxicity investigations, this complex could be considered as an alternative antibiotic agent. Key words: Cu(II)chloride salts, mononuclear complex, antimicrobial activity, 1,10-phenantrolein, acetamide.	en_US
dc.language.iso	en_US	en_US
dc.subject	chemistry	en_US
dc.title	SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITIES OF MONONUCLEAR COPPER (II) COMPLEX OF 1, 10-PHENANTHROLEIN AND ACITAMID LIGANDS	en_US
dc.type	Thesis	en_US