Ron(Iii) Complex With Guanide, Benzoic Acid, And 1, 10-Phenanthroline: Synthesis, Characterization And Antibacterial Activity Study

Yenework, Zewdu

dc.contributor.author	Yenework, Zewdu
dc.date.accessioned	2025-07-28T12:33:26Z
dc.date.available	2025-07-28T12:33:26Z
dc.date.issued	2024-07
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/16800
dc.description.abstract	ron can bind to a range of molecules forming complexes that are suitable for use in various applications. Different ligands could be used to tune the properties of Iron. In this study, three complexes were synthesized from 1,10-phenanthroline (phen) alone as [Fe(phen)(H2O)4]Cl3 and from both 1,10-phenanthroline and benzoic acid (BA) as [Fe(phen)(BA)(H2O)3]Cl3 as well as from phen, BA and guanide (Gu) as [Fe(phen(BA)(Gu)((H2O)2]Cl2. The synthesis was checked using halide test, conductance measurement, spectroscopic (FTIR, Uv-vis) as well as thermogravimetric (TGA) and differential thermal analysis (DTA). In vitro antibacterial activities of the ligands, salt, and complexes were tested against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and they were compared with tetracycline. The complexes showed antibacterial activities against the tested pathogens. However, they showed lower activities than the reference. The target complex Fe(phen (BA)(Gu)(H2O)2]Cl2 showed inhibition zones 12±1 on S. aureus and 12±0.58mm on E.coli. It is also less active than the ligands as well as the salt. This result indicates the combination of the complex to be inappropriate to serve as antibacterial agent. However, the complex could be investigated for other applications including for electrochemical applications.	en_US
dc.language.iso	en_US	en_US
dc.subject	Chemistry	en_US
dc.title	Ron(Iii) Complex With Guanide, Benzoic Acid, And 1, 10-Phenanthroline: Synthesis, Characterization And Antibacterial Activity Study	en_US
dc.type	Thesis	en_US