Synthesis, Characterization and Antibacterial Activity Study of Cobalt(II) Complexes with 1, 10- phenanthroline and chrysin

Emeye, Tewachew

dc.contributor.author	Emeye, Tewachew
dc.date.accessioned	2025-07-28T12:11:02Z
dc.date.available	2025-07-28T12:11:02Z
dc.date.issued	2024-07
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/16795
dc.description.abstract	n this study, two complexes (one precursor and one new) were synthesized from 1,10- phenanthroline alone as [Co(phen)2(H2O)2]Cl2 and from both 1,10-phenanthroline and chrysin as [Co(phen)(chry)]Cl2.1.25H2O. The synthesis was checked using physicochemical techniques (solubility tests, molar conductivity, melting point, chloride test, metal determination and TGA) and spectroscopic techniques (UV-Vis and FT-IR). Based on the above data a tetrahedral geometry were proposed for both complexes. The In vitro antibacterial activities of the two metal complexes were tested against one Gram-positive Staphylococcus aureus (S. aureus) and one Gram-negative Escherichia coli (E.coli) bacteria using the disc diffusion method. Cobalt(II) complexes were active against Gram-negative bacteria (Escherichia coli) even though well known for their activity against Gram-positive bacteria. However the result shows the two complexes were less active compared to the commercial antibiotic drug tetracycline in all bacteria strains. Keywords: Co(II) complexes, 1,1 0-phenanthroline, Chrysin, antibacterial activity	en_US
dc.language.iso	en_US	en_US
dc.subject	Chemistry	en_US
dc.title	Synthesis, Characterization and Antibacterial Activity Study of Cobalt(II) Complexes with 1, 10- phenanthroline and chrysin	en_US
dc.type	Thesis	en_US