A Thesis on Synthesis, Characterization, and Antibacterial Activity Investigation of Bitartrate, (1, 10-Pheanathroline) Manganese (Ii) Complexes:

Abere, Mekuanent

dc.contributor.author	Abere, Mekuanent
dc.date.accessioned	2024-11-13T09:08:23Z
dc.date.available	2024-11-13T09:08:23Z
dc.date.issued	2024-10
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/16151
dc.description.abstract	In this study, a new Manganese (II) complex with tartaric acid (C 4 H 6 O ) and 1, 10-phenanthroline (C 12 N 2 H 8 6 ) ligands were synthesized and characterized using various Physico-chemical (molar conductance, solubility test, and melting point gravimetric analysis) and spectroscopic techniques (FTIR, UV-Vis). Based on the Physico-chemical and spectroscopic data octahedral geometry were proposed for both of complexes. Moreover, in - vitro antibacterial activity was also tested on two Gram positive (S. aureus, S.epidermidis) and two Gram negative (E. coli and K. pneumonia) bacteria using disc diffusion method [Mn (C 4 H 5 O 6 ) phen] complexes showed better activities on Streptococcus epidermidis than the other bacteria. The free ligand 1, 10-phenanthroline demonstrated better activity than other complex and ligands in all types of bacteria. Thus, after cytotoxicity and in vivo test, these complexes may be used as alternative drug against the above mentioned bacteria. 2	en_US
dc.language.iso	en_US	en_US
dc.subject	Chemistry	en_US
dc.title	A Thesis on Synthesis, Characterization, and Antibacterial Activity Investigation of Bitartrate, (1, 10-Pheanathroline) Manganese (Ii) Complexes:	en_US
dc.type	Thesis	en_US