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Background: Hirschsprungs disease is one of the cause of intestinal obstruction in pediatric patients that requires surgical correction. However, the surgical management sometimes ends with unfavourable outcomes characterized by fatal and nonfatal postoperative complications.
Objectives: To identify operative outcomes and associated factors in Hirschsprungs disease patients at TGSH and FHCSH, Bahir Dar Ethiopia, 2015 E.C.
Method: Institution based cross-sectional study of all biopsy proven Hirschsprungs disease patients in TGSH admitted from January ,2011 E.C to April ,2014 E.C and FHCSH from September 2007 E.C to January 2011 E.C will be included. Patients who fulfill the inclusion criteria will be selected by systematic random sampling from registration logbook. The collected data will check for completeness. The collected data will be coded, entered into EPI data version
3.1 software, and exported to statistical product and service solutions (SPSS) version 25 software packages for further analysis. Descriptive statistics will be used to summarize the data in the form of frequency, mean, standard deviation (SD), and cross-tabulation. Binary logistic regression analyses will be carried out to identify the association between the outcome variable and independent variables. A p-value <0.05 will be considered statistically significant. Adjusted odds ratio (AOR) with 95% confidence intervals (CI) will be used. The results of the analysis will be presented in texts, tables, and figures.
Result: From 218 study participants (HSD patients),156(71.2%) were males and 62(28.8%) females. About 31.2% of HSD patients had unfavorable outcomes. Late presentation after one year of age (p=0.002, AOR=5.002, 95% CI [1.820, 13.750]), the presence of down syndrome (p=0.006, AOR=7.442, 95% CI [1.796, 30.839]), preoperative HAEC (p=0.044, AOR=2.532, 95% CI [1.025, 6.254]) and long segment HSD (p=0.026, AOR= 7.176, 95% CI [1.267, 40.638])
are significantly associated with post-operative unfavorable outcomes of HSD patients.
Conclusion: from this study majority of patients had favorable post-operative outcomes (68.8%). The most frequently observed post-operative complication from this study was constipation which occurs in 18(8.2%) patients after definitive operation.
Keyword: HSD, HAEC, outcome, down syndrome …………………. |
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