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BACKGROUND-The mortality and neurologic sequelae associated with acute bacterial meningitis (ABM) Remain high despite advances in medical care. In our country information on clinical outcomes of meningitis and associated risk factors is limited. The objective of this study was to evaluate short-term treatment outcome in patients treated as meningitis in children beyond neonatal age at Tibebe Ghion specialized Hospital to identify factors that could be focused on to improve outcome in this setting.
METHODS-A hospital based cross sectional study design was conducted among 215 children in Tibebe Ghion comprehensive specialized hospital. Simple random sampling method was used to select charts and the data was collected by using structured checklists. Data were checked for completeness, inconsistencies and was entered to SPSS Version 25 for analysis. Bivariate and multivariate logistic regression was used to identify factors associated with treatment outcomes of meningitis. The findings were presented with p-values, and odds ratio with its 95% confidence level. P-value of less than 0.05 was used to declare significance level.
RESULT: About 19.1% children beyond neonatal age with meningitis developed poor outcomes: developed complication and died. In this study, age [AOR= 17.931(2.983, 107.779)], the presence of seizure at presentation [AOR= 4.321(1.250, 14.941)], CSF cell count [AOR= 4.218(1.171, 15.194)] and nutritional status [AOR= 2.737(1.049, 7.141)] were the determinant factors for clinical outcome of meningitis.
CONCLUSION: In this study, nearly one in five of children beyond neonatal age with meningitis developed poor outcomes. Our finding also indicated that age, the presence of seizure at presentation, CSF cell count, and nutritional status were associated with poor outcome of meningitis. Therefore, creating community awareness about risk factors of meningitis, early diagnosis and treatment of cases and improving nutritional supplementation are recommended to improve the clinical outcome of children affected with meningitis.
Keywords: Clinical outcomes, meningitis, children, Tibebe Ghion Specialized Hospital, Ethiopia. |
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