PHYTOCHEMICAL SCREENING, INVITRO-ANTI-OXIDANT AND ANTI BACTERIAL ACTIVITIES OF THE STEM EXTRACTS OF JASMINUM  ABYSSINICUM (TEMBELEL) PLANT

GASHA, HANA

dc.contributor.author	GASHA, HANA
dc.date.accessioned	2021-07-27T07:58:42Z
dc.date.available	2021-07-27T07:58:42Z
dc.date.issued	2021-07-27
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/12269
dc.description.abstract	Traditional medicinal plants are rich in bioactive compounds or secondary metabolites. Jasminum is one of the ethno-medicinal plants that have a potential of therapeutic functions. Traditional medicine has not only gained popularity and approval, but it is sometimes the only system available in many rural areas. In this study, successive extraction of stem of Jasminum abyssinicum (J.abssynicum) was carried out by using different solvent system and followed by qualitative phytochemical analysis, total flavonoid and phenolic content determination, antioxidant and antibacterial activity tests of the extracts. Qualitative phytochemical screening of the crude extracts obtained from the stems of the plant indicated the presence of alkaloids, flavonoids, phenols, glycoside, steroids, terpenoids, saponins and tannins. The highest total phenolic and total flavonoid content was obtained in ethanol extract, followed by dichloromethane and petroleum ether extract. All stem extracts of J. abyssinicum exhibited antioxidant activity as revealed by DPPH assays. All stem extracts showed antibacterial activity against gram positive (Staphylococcus aureus, Streptococcus pyogenes) and gram negative (Escherichia coli, K. pneumonia) bacteria. The result showed that the extracts of the plant exerted more bactericidal effect on gram positive bacteria than gram negative bacteria. Key words: antioxidant activity, antibacterial activity, Jasminum abyssinicum, phytochemical, total phenol and total flavonoid content.	en_US
dc.language.iso	en	en_US
dc.subject	Chemistry	en_US
dc.title	PHYTOCHEMICAL SCREENING, INVITRO-ANTI-OXIDANT AND ANTI BACTERIAL ACTIVITIES OF THE STEM EXTRACTS OF JASMINUM ABYSSINICUM (TEMBELEL) PLANT	en_US
dc.type	Thesis	en_US