dc.description.abstract |
The distribution of blood groups was different from place to place and may not be found
in similar numbers even among ethnic groups. Frequency distribution of blood groups is
important for modern medicine, genetic research, anthropology, ancestral relations of
humans and forensic science. The aim of this study was to determine the allelic, genotypic
and phenotypic frequency distribution of ABO and Rh blood groups among students
attending in Tagel preparatory and high school in Simada woreda, Ethiopia from
September to August 2020. Blood samples were taken from 384 volunteer students by
finger-pricks and blood groups were determined by haemagglutination method using
commercially available anti-sera A, B, and Rh (D). Descriptive statistics was used to
calculate percentage frequencies of blood phenotype. The genotypic and allelic
frequencies of the blood groups were calculated from the observed phenotypes under the
assumption of Hardy–Weinberg equilibrium. In the ABO system, type O was the most
prevalent (34.63%) followed by A (32.03%), B (23.95%) and AB the least (9.37%). In case
of Rh system, most of the students were Rh+ (96.1%) and the rest were Rh-(3.9 %). The
allelic frequencies of O (Io
), B (IB
) and A (IA
) were 0.58, 0.22 and 0.19, respectively. While
allelic frequencies of the Rh blood group of D and d were 0.803 and 0.197, respectively.
Genotypic frequencies of OO, AA, AO, BB, BO, and AB were 0.336, 0.048, 0.255, 0.036,
0.220 and 0.084 respectively. While the genotypic frequency of DD, Dd and ddwere0.64,
0.31, and 0.039 respectively. The present study gives baseline information regarding the
management of blood bank and transfusion services in the community. Large sample size
with different areas is recommended to make strong generalizations.
Key words: Blood group, Tagel preparatory and high school, prevalence, Rh, ABO |
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