Alcoholic beverage quality is significantly affected by inorganic ion and organic compounds content. Wine is an alcoholic beverage that contains products of the fermentation of the juice from the grapes. This study evaluates the concentrations of metals and tannin in wine; seven different brands of wine from different supermarket in Bahir Dar city were analyzed. The metals concentration was determined using inductively coupled plasma optical emission spectrometry (ICP-OES). Redox titration method was selected to determine the tannin content. The concentrations of major metals occur in the following order: K > Mg > Ca > Na There is also a significance difference between metals except Rift Valley cabernet sauvignon dry red and Rift Valley Syrah dry red and for the minor metals the following results were recorded Fe (3.408– 7.649), Zn (1.893 –9.336) and Mn (1.335 –1.823) in mg/L, followed by copper (0.279 –0.388 mg/L), nickel (0.243 –1.177mg/L), cobalt (ND) and chromium (0.0125 –0.264 mg/L). The toxic metal lead was in the range of 0.116 –0.417 mg/L while cadmium was not detected in this study (ND). The levels of metals in the castle Ethiopian wines were found to be comparable with wines of some other countries and no significant difference (p > 0.05) at 95% confidence level was observed for Cr and Ni in all wine brand analyzed except Acacia Medium Sweet White for Cr and Rift Valley Syrah dry red and Rift Valley merlot dry red for Pb. The levels of tannins in Ethiopian castle wine are in the range of 0.0172 to 0.0804% and red wines have greater tannin than white wine.