xi Intestinal parasitic infections (IPIs) are prevalent throughout the tropics and sub tropics, especially among poor countries including Ethiopia and school children are one of the highly susceptible groups. The effective prevention and control of intestinal protozoa and helminthic infections require identification of local risk factors. Therefore the aim of this study was to assess the prevalence of intestinal parasitic infections and associated risk factors among school children in Jaragedo town Schools, South Gondar Zone. A cross sectional study was conducted from October to April 2011 involving 396 students from two different schools (one elementary and one secondary school). Students were selected by stratified simple random sampling method. Questionnaire purposively structured to collect socio- demographic and socio-economic data of study subjects was developed based on the known risk factors. The stool samples were examined microscopically using formal-ether concentration technique. Data collected were fed into SPSS (Statistical Products and Service Solutions) version 20 software. Descriptive statistics was used to give a clear picture of population characteristics. Logistic regression was also invoked using SAS to determine the relationship between dependent variables (primarily infections) with independent (explanatory) variables. In the present study 65.4% was an overall prevalence of intestinal parasitic infections. E.histolytica/dispar was the most prevalent intestinal parasite with 27% rate; followed by G lamblia (17.4%) other parasites could not infect more than 5% of the study subjects. Generally, parasitism did not vary between the sexes (a difference of only about 2%). Grade level of students, water source, habit of consuming raw meat, level income had strong effect on intestinal parasitic infections (P-Value < 0.05). Other explanatory variables were not significant (P > 0.05). High prevalence of these parasites is good indicator of improper disposal of waste, low socio economic level, low living standard and it also reflects the use of water with poor quality. Therefore intervention strategies should be addressed to minimize rate of infection in the study area. Key words- Intestinal parasitic infections, Jaragedo, prevalence, School children