Thesis and Dissertations

Prevalence of Peripheral Neuropathy and Associated Factors among Adults with Type 2 Diabetes In Tibebe Ghion Comprehensive Specialized Hospital, Northwest Ethiopia 2025.

Sun, 01 Feb 2026 00:00:00 GMT

Prevalence of Peripheral Neuropathy and Associated Factors among Adults with Type 2 Diabetes In Tibebe Ghion Comprehensive Specialized Hospital, Northwest Ethiopia 2025. Mequaninet, Misganaw ABSTRACT Background: Diabetic peripheral neuropathy is a leading microvascular complication causing significant morbidity, yet data in Northwest Ethiopia remains limited. Timely identification is essential to prevent ulcers and amputations. Objective: The aim of this study is to assess the prevalence of peripheral neuropathy and associated factors among adults with Type 2 diabetes at referral clinic in Tibebe Ghion Comprehensive Specialized Hospital, Northwest Ethiopia 2025. Methods: A hospital-based cross-sectional study was conducted at Tibebe Ghion Comprehensive Specialized Hospital diabetes follow up clinic on 403 type2 diabetic patients. Data were collected by using pretested structured questioner and checked and exported to SPSS version 27 for analysis. Both bivariate and multivariate binary logistic regressions were employed to identify factors associated with diabetic peripheral neuropathy. A variable having a p value of < 0.25 in the bivariate model was subjected to multivariate analysis to avoid confounding variable’s effect. Adjusted odds ratios were calculated at 95% confidence interval and considered significant with a p value of ≤ 0.05. Results:This study finding showed that the prevalence of DPN was 28.5% (95% CI: 24.1% –33%) among study participants.According to the multivariate logistic, Drinking of alcohol now or in the past(AOR =4.33; (95% CI: 1.71, 11.00), no formal education (AOR =10.98; (95% CI: 1.66, 72.62), attending up to primary education (AOR =24.80; 95% CI:3.25, 189.32), physical inactivity (AOR =2.02; 95% CI: 1.14, 3.55), Good foot self care practice (AOR =0.36; 95% CI:0.17, 0.77), the presence of HTN (AOR=4.63; 95% CI: 2.14, 9.99), Dyslipidemia (AOR =2:79; 95% CI: 1.01, 7.66), Diabetic retinopathy (AOR=8.04; 95% CI: 1.53, 52.83), Diabetes Kidney disease (AOR=8.98; 95% CI: 2.09, 30.91) and participants on only insulin therapy(AOR=3.66; 95% CI: 1.32, 10.11) were independent predictors of diabetic peripheral neuropathy among study participants. Conclusion: Lower educational level, the presence of comorbidities and other microvascular complications were strongly associated with it. Targeted early screening and intensive management of comorbidities, alongside promoting foot self-care, alcohol cession and physical activity, are crucial to reducing the burden of diabetic peripheral neuropathy.

In-hospital mortality of acute respiratory distress syndrome and its associated factors in adult intensive care unit of specialized hospitals in Bahir Dar, Ethiopia

Sun, 01 Feb 2026 00:00:00 GMT

In-hospital mortality of acute respiratory distress syndrome and its associated factors in adult intensive care unit of specialized hospitals in Bahir Dar, Ethiopia Gashaw, Bekalu ABSTRACT Background: Acute respiratory distress syndrome (ARDS) is an acute condition marked by bilateral lung infiltrates and hypoxemia within one week of an inciting event. Despite advances in critical care, ARDS continues to be associated with high mortality and prolonged hospital stays. Mortality is influenced by patient characteristics, disease severity, treatment strategies, and complications. However, data on ARDS outcomes in Ethiopia, particularly in the Amhara region, remain limited. Objectives:This study aimed to determine in-hospital mortality of ARDS and associated factors in intensive care units of TibebeGhion and FelegeHiwot Specialized Hospitals, Bahir Dar, Ethiopia, from November 2020 to November 2025. Methods: A retrospective cohort study was conducted using 374 medical records of adult ARDS patients. Data were collected from December 15, 2025, to January 10, 2026, using a structured data extraction tool. Data were entered into Kobo Toolbox and analyzed using SPSS version 27. Bivariate and multivariable logistic regression analyses were performed to identify factors associated with in-hospital mortality. Results:The study demonstrated that in-hospital mortality of ARDS was 63.1%(95% CI: 58.2%–68.0%). Multivariable logistic regression analysis identified;low GCS (8–12: AOR = 2.23, 95% CI 1.16–4.30; <8: AOR = 2.83, 95% CI 1.03–7.80), moderate (AOR = 2.20, 95% CI 1.14–4.26) and severe ARDS (AOR = 3.02, 95% CI 1.49–6.10), extra-pulmonary sepsis (AOR = 2.98, 95% CI 1.13–7.91), liberal fluid management (AOR = 3.27, 95% CI 1.55–6.91), and complications such as VAP(AOR = 2.95, 95% CI 1.02–8.54) and sepsis (AOR = 4.28, 95% CI 2.04–8.98) as independent predictors of in-hospital mortality. Conclusion: The study demonstrated that in-hospital mortality was higher than rates reported in developed countries and in most developing nations. Various factors were identified as independent predictors of in-hospital mortality. These findings emphasize the urgent need for targeted interventions to enhance the quality of critical care for patients with ARDS.

Magnitude of elective surgical case cancellation and its associated factors among elective surgical cases at Tibebe Ghion specialized hospital, Bahir Dar, Ethiopia

Sun, 01 Mar 2026 00:00:00 GMT

Magnitude of elective surgical case cancellation and its associated factors among elective surgical cases at Tibebe Ghion specialized hospital, Bahir Dar, Ethiopia Yayeh Meshesha, Yibeltal ABSTRACT Background: Elective surgical case cancellation refers to any elective surgical casethat is booked into the operation theatre list on the day prior to surgery, but is not operated upon as scheduled. Elective surgical case cancellation is common and canhave significant adverse effects. The cancellation of planned surgeries causes prolonged wait times, harm to patients, and is a waste of scarce resources. Reasonsfor cancellations are complex because they are related to patients, organizational issues, and clinical staff. OBJECTIVE: To assess Magnitude of Elective Surgical Case Cancellation and Its Associated Factors among Elective Surgical Cases at Tibebe Ghion Specialized Hospital, Bahir Dar, Ethiopia from September 1, 2025 to January 30, 2026. Methods: Institution based Prospective study design was used.A structured research tool was used to collect all necessary data from daily schedule list. The collected data were entered into Kobo Toolbox, and thenexported to SPSS version 23 for analysis and descriptive statistics was used to present the result. All elective surgical cases scheduled but canceled due to some reason (n=107) to undergo elective surgical procedures were included in this study. Result: A total of 1150 patients were scheduled for elective surgical operations. Of these, 107(9.30%) were canceled. About 61(57 %) of males and 46(43 %) of females were cancelled. Orthopedic surgery had the highest rate of cancellations 25(23.36%) followed by Urological surgery 18(16.82%).Of the cancellations, 29 (27.10%) were due to management-related reasons, 24 (22.43%) were due to medical illness, and 17 (15.89%) were due to lack of time Conclusion and Recommendation: Management related, medical illness, and shortage of time were the main causes of cancellation of elective surgical operations in our hospital during the study period. Concerned bodies should bring a sustainable change and improvement to prevent unnecessary cancellations and enhance cost effectiveness through communications, careful preoperative planning, and efficient utilization of time management and available hospital resources.

Pattern, treatment outcome and associated factors of non-traumatic shock among patients presenting to adult emergency department of Tibebe Ghion specialized hospital from January 1, 2022, to December 31, 2025

Sun, 15 Feb 2026 00:00:00 GMT

Pattern, treatment outcome and associated factors of non-traumatic shock among patients presenting to adult emergency department of Tibebe Ghion specialized hospital from January 1, 2022, to December 31, 2025 Mengist, Melaku Abstract Background: Non-traumatic shock is a major cause of morbidity and mortality in emergency departments worldwide. In resource-limited countries like Ethiopia, where emergency care systems experience significant constraints, early identification and management of shock are critical yet often challenging. However, evidence on its patterns, outcome, and predictors of mortality remains limited in Ethiopia and the study area as well. Objective: This study aimed to assess the pattern, treatment outcome, and associated factors of non-traumatic shock among adult patients presenting to the emergency department of Tibebe Ghion Specialized Hospital, Ethiopia, between January 1,2022, and December 31, 2025. Methods: A hospital-based retrospective cross-sectional study was conducted among adult patients admitted with non-traumatic shock between January 1, 2022, and December 31, 2025. Medical records were reviewed to extract socio-demographic, clinical, laboratory, and treatment-related data. Data quality was ensured through pretested tools and regular supervision. Descriptive statistics were used to summarize patient characteristics. Multivariable binary logistic regression analysis was performed to identify independent predictors of mortality, with adjusted odds ratios (AOR) and 95% confidence intervals (CI). Results:A total of 422 patient cards were identified for assessment, of which 32 incomplete recordswere excluded, resulting in 390 eligible cards and a response rate of 92.4%. Septic shock was the most common type of non-traumatic shock (43.1%),followed by hypovolemic shock (33.1%) and cardiogenic shock (14.9%). The overall mortalitywas 17.7%. Night-time presentation to the emergency department (AOR = 2.0, 95% CI: 1.10–3.64), use of vasopressors (AOR = 2.28, 95% CI: 1.04–5.01), elevated creatinine levels >1.2 mg/dl (AOR = 4.34, 95% CI: 1.72–10.9), and presence of chronic liver disease(AOR = 3.81, 95% CI: 1.40–10.4) were significantly associated with mortality. Conclusion and Recommendation: Non-traumatic shock remains a significant contributor to mortality in the emergency department, with septic shock being the most common type. Mortality is strongly influenced by both patient and system-related factors. Therefore, strengthening night-shift staffing, improving renal monitoring capacity, ensuring wise use of vasopressors, and prioritizing care for patients with chronic liver disease are essential strategies for reducing mortality.